S100A1 anticorps

N° du produit ABIN356322

Cet anticorps anti-S100A1 est un anticorps Souris Monoclonal détectant S100A1 dans IF, IHC (p), FACS et IHC (fro). Adapté pour Humain, Souris, Rat et Boeuf (Vache).

Aperçu rapide pour S100A1 anticorps (ABIN356322)

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: S100217

Détail du produit anti-S100A1 anticorps

Specificité: This antibody stains schwannoma, ependymomas, astrogliomas, almost all benign and malignant melanoma and their metasis.
Cellular Localization: Cytoplasmic.

Attributs du produit: Synonyms: S100 Calcium binding protein, S-100 protein, S100A, S100B, S-100 protein alpha chain,S-100 protein beta chain, Astrocyte Marker, S-100 protein alpha subunit, S-100 proteinbeta subunit, S100 Alpha, S100 Beta

Purification: Protein A Chromatography.

Immunogène: Purified bovine S100 protein. Remarks: Molecular weight of antigen: ~22 kDa.

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. FFPE tissue section requires antigen retriever (boiling tissue in 10 mM citrate, pH 6.0 for 20

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur S100A1

Antigène: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Autre désignation: S100A1

Sujet: S100 protein is a type of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100 % Soluble in ammonium sulfate at neutral pH . Most S100 proteins are homodimeric, consisting of two identical polypeptides held together by non-covalent bonds. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Although S100 proteins are structurally similar to calmodulin, they differ in that they are cell-specific, expressed in particular cells at different levels depending on environmental factors. To contrast, calmodulin is a ubiquitous and universal intracellular Ca++ receptor widely expressed in many cells.S-100 is normally present in cells derived from the neural crest (Schwann cells, melanocytes, and glia cells), chondrocyte, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. It may be present in some breast epithelial cells.Synonyms: Astrocyte Marker, S-100 protein, S-100 protein alpha chain, S-100 protein alpha subunit, S-100 protein beta chain, S-100 protein beta subunit, S100 Alpha, S100 Beta, S100 Calcium binding protein, S100A, S100B

ID gène: 528735

UniProt: P02639

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins